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Ȩ Ȩ > ¿¬±¸¹®Çå > ±¹³» ³í¹®Áö > Çѱ¹Á¤º¸°úÇÐȸ ³í¹®Áö > Á¤º¸°úÇÐȸ³í¹®Áö (Journal of KIISE)

Á¤º¸°úÇÐȸ³í¹®Áö (Journal of KIISE)

Current Result Document :

ÇѱÛÁ¦¸ñ(Korean Title) ¸ÖƼ ¸ð´Þ µ¥ÀÌÅ͸¦ ÀÌ¿ëÇÑ Çѱ¹Çü ÁÖ¿ä ¿ì¿ï Àå¾Ö Áø´Ü ¹× Ä¡·á ¸ðµ¨
¿µ¹®Á¦¸ñ(English Title) Diagnostic and Therapeutic Model for Korean Major Depressive Disorder Using Multi-Modal Data
ÀúÀÚ(Author) ÃÖ¿ëÈ­   ±è¾Æ¶÷   Àü¹ÎÁö   ±è¼±±Ô   ÇѱԸ¸   ¿øÀº¼ö   ÇÔº´ÁÖ   °­Àç¿ì   Yonghwa Choi   Aram Kim   Minji Jeon   Sunkyu Kim   Kyu-Man Han   Eunsoo Won   Byung-Joo Ham   Jaewoo Kang  
¿ø¹®¼ö·Ïó(Citation) VOL 46 NO. 01 PP. 0071 ~ 0076 (2019. 01)
Çѱ۳»¿ë
(Korean Abstract)
¿ì¿ïÁõÀº Çö´ë »çȸ¿¡¼­ °¡Àå ÈçÇÑ Á¤½ÅÁúȯ Áß Çϳª·Î, ¹Ýº¹µÇ´Â Àç¹ß¿¡ µû¸¥ ¸¸¼ºÈ­·Î ÀÎÇØ »çȸÀûÀÎ ºÎ´ãÀ» Áõ°¡½ÃŲ´Ù. ±×·¯³ª ´Ù¾çÇÑ ¿äÀεéÀÌ º¹ÇÕÀûÀ¸·Î °ü¿©ÇÏ´Â Áúº´À̱⠶§¹®¿¡ ¿©·¯ ¿äÀÎÀ» È¿À²ÀûÀ¸·Î °í·ÁÇÒ ¼ö ÀÖ´Â ±â°èÇнÀ ¸ðµ¨ÀÌ ÇÊ¿äÇÏ´Ù. º» ³í¹®¿¡¼­´Â ±âº» Á¤º¸, MRI, À¯ÀüÀÚ, ÀÎÁö °Ë»ç ÀÇ 4°¡Áö ¸ÖƼ ¸ð´Þ µ¥ÀÌÅ͸¦ ÀÌ¿ëÇØ ¿ì¿ïÁõ ¿©ºÎ¸¦ Áø´ÜÇÏ°í Ç׿ì¿ïÁ¦ ¹ÝÀÀÀÇ Á¤µµ¸¦ ¿¹ÃøÇÒ ¼ö ÀÖ´Â ¸ð µ¨À» Á¦¾ÈÇÏ¿© ¿ì¿ïÁõ Áø´ÜÀÇ °æ¿ì AUROC Á¡¼ö 0.923, Ç׿ì¿ïÁ¦ ¹ÝÀÀ¼º ¿¹ÃøÀÇ °æ¿ì MSE 0.08ÀÇ Á¤È® µµ¸¦ ¾ò¾ú´Ù. ±×¸®°í Á¦¾ÈÇÑ ¸ðµ¨ÀÇ °á°ú¸¦ Á¤·®ÀûÀ¸·Î ºÐ¼®ÇÏ¿© ȯÀÚÀÇ µ¥ÀÌÅ͸¦ Ãß°¡ÇÒ¼ö·Ï Á¤È®ÇÑ Áø´Ü ¹× ¾à¹° ¹ÝÀÀ¼º ¿¹ÃøÀÌ °¡´ÉÇÔÀ» È®ÀÎÇÏ°í, Á¤¼ºÀûÀ¸·Î ºÐ¼®ÇÏ¿© ¿ì¿ïÁõ¿¡ °üÇØ ±âÁ¸¿¡ ¾Ë·ÁÁø ÁÖ¿ä ¿äÀÎ À» ã´Â °Í»Ó ¾Æ´Ï¶ó »õ·Î¿î °¡¼³À» Á¦½ÃÇÏ¿´´Ù.
¿µ¹®³»¿ë
(English Abstract)
Depression is one of the most common mental illnesses in the modern society, and it increases the social burden due to repeated recurrences. However, since there are many pre-disposing factors that cause depression, there is need to develop a machine-learning model that examine these factors effectively. In this paper, we propose a model that can diagnose depression and predict the degree of antidepressant response using four multi modal data including basic information, MRI, genetics, and cognitive test. The model achieved 0.923 AUROC score for diagnosis and 0.08 MSE for prediction of antidepressant response. In addition, the results of the proposed model were quantitatively analyzed, and it confirmed that accurate diagnosis and drug response prediction are possible when the patient¡¯s data is added. Qualitative analysis was also conducted to provide new hypotheses as well as findings on the main factors causing depression.
Å°¿öµå(Keyword) ¿ì¿ïÁõ   Áø´Ü ¸ðµ¨   ¾à¹° ¹ÝÀÀ¼º   ±â°è ÇнÀ   depression   diagnostic model   drug response   machine learning  
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